Take Two is keeping the publishing rights to Duke Nukem Forever, and Apogee Software have just confirmed that the situation at 3D Realms has not affected the development for the new handheld titles for PSP and Nintendo DS. The handheld will be developed by Frontline Games'.
Duke Nukem Forever has been trying to release for almost 12 years, and even a short teaser was released in late 2007 (Seen Below).
What the future may hold for the Gun-slinging, glasses wearing, balls of steel hero, only time will tell. But if you are interested you could always fill his shoes.
Shame though, seeing as the previous versions in the series were actually quite fun. Even the 2D version of it.